The grant will fund a study on chronic pain after traumatic brain injury in collaboration with the University of Washington and eight other Traumatic Brain Injury Model Systems funded institutions.
Craig Hospital, a world-renowned rehabilitation hospital for people with spinal cord and/or brain injuries, has been awarded a $3 million research grant from the National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR).
The project, titled “Characterization and Treatment of Chronic Pain after Moderate to Severe Traumatic Brain Injury,” will leverage an existing successful research network – the Traumatic Brain Injury Model Systems (TBIMS) – to determine chronic pain classification, prevalence, location, duration, and associations with demographic, injury severity, current level of functioning and comorbidities in participants followed in 10 centers participating in the NIDILRR and Department of Veterans Affairs TBIMS databases. The study will be led by two investigators at Craig Hospital, Dr. Cindy Harrison-Felix and Dr. Kimberley Monden, and one investigator at the University of Washington, Dr. Jeanne Hoffman. The study also involves a partnership with the Rehabilitation Outcomes Research Section at the James A. Haley VA Hospital in Tampa, Florida.
Results from this study will provide a more detailed picture of the problem of chronic pain after TBI by examining the types of pain that occur after TBI as well as the frequency of comorbid conditions. Identifying extreme phenotypes, such as demographic, individual and treatment factors associated with those who have chronic pain but have minimal interference compared to those who are significantly impacted by pain, will allow researchers to identify treatment targets and advance a personalized medicine approach to treatment.
Researchers will produce educational materials on chronic pain and pain treatment to benefit patients, family members, clinicians and policymakers. Data from this study will have a direct impact on clinical practice, informing future work and promoting understanding of constituent factors in extreme phenotypes.